Endocrine Abstracts

Introduction: Premature newborns are defined as babies born before 37 weeks of pregnancy and after 22 weeks of pregnancy as a viability limit. This study aimed to analyse growth characteristics at the age of second and third age and the prevention of metabolic diseases that may occur in adult age at an early phase.Methods: This study was conducted as a retrospective cohort study between May 2021 and October 2021 in 18 different Outpatient Clinics in Patn...

Introduction: The most prevalent hereditary disease of adrenal steroid production is congenital adrenal hyperplasia (CAH), which is caused by a 21-hydroxylase deficiency. With or without salt wasting, patients with the typical form of CAH exhibit androgen excess. Leptin participates in endocrine and metabolic processes in addition to controlling energy balance. This study examined BMI values for children and teens with CAH in comparison to population-based benchmarks. Current ...

Introduction: Metabolic syndrome (MetS) consists of a constellation of metabolic abnormalities which include central obesity, hyperglycemia plus insulin resistance, high triglycerides plus low high-density lipoprotein (HDL) cholesterol and hypertension. A developing collection of proof proposes that metabolic condition is related to endocrine problems including thyroid brokenness. Thyroid brokenness in metabolic condition patients might additionally add to cardiovascular illne...

Short stature in thalassemia major: multiple aetiologies.A 24 year old Asian male with beta-thalassemia major was referred with symptoms of tiredness, weight gain, muscle weakness and depression. He had been treated elsewhere with blood transfusions, desferrioxamine and had undergone a splenectomy. He was known to have underlying cardiac dysfunction and was diagnosed to have hypogonadotrophic hypogonadism at the age of 17 years and primary hypothyroidism...

Primary Hyperparathyroidism is known to present with protean manifestations leading to misdiagnosis in the initial stages of the disease. In the developing world, most of the cases are detected late when they manifest with severe symptomatic metabolic bone disease or renal stones. Distal Renal Tubular Acidosis is a rare complication of primary hyperparathyroidism and should be looked for, in cases presenting with nephrolithiasis. Nuclear scintigraphy accurately localizes the t...

Introduction: Multiple specialities teach and perform ultrasound-guided fine-needle aspiration biopsy (USG-FNA) of thyroid nodules, including Radiology, Endocrinology, and Pathology. Contrasts in cytopathology results might connect with various USG-FNA procedures just as contrasts in the knobs assessed. This study planned to play out a nitty-gritty investigation of USG-FNA results among these different showing administrations at a solitary scholarly clinical focus.<p class...

The foetus of a mother with previous or current Graves disease is at risk of developing thyrotoxicosis. The mother can act as a bioassay to diagnose foetal thyrotoxicosis. We describe the difficulties in managing foetal thyrotoxicosis in a mother who could not act as a bioassay because of previous Graves disease treated by total thyroidectomy.A 35year old woman fell pregnant 3 months after a total thyroidectomy for relapsed Graves disease and concomitant...

Introduction: Bone marrow is an abundant source of adult stem cells that can differentiate into various cell types. Administration of mesenchymal stem cells (MSCs) in irradiated diabetic rat model has transiently shown to decrease blood glucose level. This study examines the effect of high dose and multiple injections of MSCs on glycaemic profile, their localisation and regeneration of islet in diabetic Wistar rat.Methods: The study was carried out in ma...

Introduction: There is a growing interest in cell-based therapies in T2DM as β-cell failure is progressive and inexorable. This study evaluates the efficacy of autologous bone marrow-derived mesenchymal stem cell transplantation (ABM-MSCT) in T2DM.Methods: This prospective, randomised, single-blinded placebo-controlled study enrolled 20 patients with triple oral hypoglycaemic drug failure and requiring insulin ≥0.4 Units/kg per day for achievi...

The number of the people with type 2 diabetes is increasing globally, therefore there is an increasing need to identify diabetes earlier and more efficiently. Nearly 80% of people with diabetes live in low and middle income countries (LMICs). Traditionally, we have relied on glucose-based criteria (fasting, postprandial, and random) to make the diagnosis of diabetes; however, HbA1c has recently been endorsed as a diagnostic test, as superior alternative to glucose-based criter...